Chanel Oberlin is the queen of Kappa Kappa Tau sorority and the most popular girl on campus, with the hottest boyfriend, Dickie Dollar Scholar's President, Chad Radwell. Chanel has her own set of minions that go by the names of Chanel #2, Chanel #3, and Chanel #5 who do everything she asks of them. She has the biggest room in the Kappa house and two story walk in closet full of every designer's piece of clothing you could imagine. Chanel is head bitch in charge at Wallace University and a force to to be reckon with.
In 1995, a terrible accident occurred in the Kappa Kappa Tau sorority at Wallace University, a mystery that was never solved. In present day, Chanel Oberlin is the new president of the sisterhood, and with the help of her minions, Chanel #2, Chanel #3, and Chanel #5, make Kappa a house full of glamour, beauty, and evil. Tired of this, the dean of the campus, Cathy Munsch, requires The Chanels to accept anyone who wants to be part of Kappa. This opens place to people like Grace Gardner, a girl trying to discover more about her mother and Kappa's past with the help of her love interest Pete Martínez and overprotective father, Wes Gardner. Zayday Williams, Grace's genius best friend who wants to become Kappa's new president, Hester Ulrich, who suffers of scoliosis and is obsessed with Chanel, Jennifer, a candle vlogger, Sam, a tomboy lesbian, and Tiffany DeSalle , a deaf Taylor Swift obsessed girl. This threatens Chanel's popularity and Kappa's reputation, causing major problems in her relationship with Chad Radwell, the rich leader of the Dickie Dollar Scholars fraternity and most popular guy in the University.
Full of anger, Chanel and her minions try to make the new pledges' time at the house a living hell, but what begins as a dirty game, ends in a series of murders caused by Red Devil, a serial killer who hides behind the mask of the university mascot. The race for survival begins in an environment where anyone can be attacked, anyone can die, and anyone can be the killer. Will the Kappa girls discover the true identity of the psychopathic murderer and come out alive?